Weakness, Numbness and Urinary Incontinence in an 11-Year-Old Female. (June 2022)

• Record Type: Journal Article
• Authors: Isaac Maximo, Larissa Maria; March, Amanda; Lam, Suet Kam
• Is Part Of: Global pediatric health. Volume 9(2022)
• Publication Date: 2022-06
• Subjects: acute disseminated encephalomyelitis -- SARS-CoV-2 infection -- demyelinating disease; Pediatrics -- Periodicals; Children -- Health and hygiene -- Periodicals; 618.92
• DOI: 10.1177/2333794X221106165
• Languages: English
• ISSNs: 2333-794X

Abstract

Acute disseminated encephalomyelitis (ADEM) affects the central nervous system (CNS) via a rapid and auto-immune process. It has been associated to viral and bacterial infections, as well as after immunization. Since the beginning of the SARS-CoV-2 (COVID-19) pandemic, reports of COVID 19 infection have been linked to ADEM. We present a case of an 11-year-old female with neurological symptoms during the acute phase of her COVID-19 illness, with MRI changes and positive Myelin Oligodendrocyte Glycoprotein (MOG) antibodies, with clinical presentation consistent of ADEM.