Lower dietary intake of magnesium is associated with more callous–unemotional traits in children. (2nd November 2022)

• Record Type: Journal Article
• Authors: Portnoy, Jill; McGouldrick, Samantha H.; Raine, Adrian; Zemel, Babette S.; Tucker, Katherine L.; Liu, Jianghong
• Is Part Of: Nutritional neuroscience. Volume 25:Number 11(2022)
• Page Start: 2314
• Page End: 2323
• Publication Date: 2022-11-02
• Subjects: Magnesium -- callous–unemotional -- vitamin b6 -- diet -- antisocial behavior -- child behavior -- child nutrition -- externalizing behavior‌; Neuropharmacology -- Periodicals; Diet -- Periodicals; Diet therapy -- Periodicals; Nutrition -- Periodicals; 615.78
• DOI: 10.1080/1028415X.2021.1963064
• Languages: English
• ISSNs: 1028-415X

Abstract

ABSTRACT: Background: Although researchers increasingly recognize the role of nutrition in mental health, little research has examined specific micronutrient intake in relation to antisocial behavior and callous–unemotional (CU) traits in children. Vitamin B6 and magnesium are involved in neurochemical processes implicated in modulating antisocial behavior and CU traits. The current study examined dietary intakes of magnesium and vitamin B6 in relation to antisocial behavior and CU traits. Method: : We enrolled 11–12 year old children ( n = 446, mean age = 11.9 years) participating in the Healthy Brains and Behavior Study. Magnesium and vitamin B6 dietary intake were assessed with three 24-hour dietary recall interviews in children. CU traits and antisocial behavior were assessed by caregiver-reported questionnaires. We controlled for age, sex, race, total energy intake, body mass index, social adversity, ADHD or learning disability diagnosis, and internalizing behavior in all regression analyses. Results: Children with lower magnesium intake had higher levels of CU traits, controlling for covariates (β = −0.18, B = −0.0066, SE = 0.0027, p < 0.05). Vitamin B6 intake was not significantly associated with CU traits (β = 0.061, B = 0.19, SE = 0.20, p > 0.05). Neither magnesium (β = 0.014, B = 0.0020, SE = 0.0093, p > 0.05) nor vitamin B6 (β = 0.025, B = 0.33, SE = 0.70, p > 0.05) were significantly associated with antisocial behavior. Conclusions: Findings suggest that low dietary intake of magnesium may play a role in the etiology of CU traits but not general antisocial behavior. More studies are needed to determine if magnesium supplementation or diets higher in magnesium could improve CU traits in children.