Clinical Recovery of Chronic Intestinal Pseudo-Obstruction With Cisapride in a Complex Pediatric Patient. (June 2013)

• Record Type: Journal Article
• Authors: Cameron, Jean-Christy F.; Vaillancourt, Régis; Major-Cook, Nathalie; Boland, Margaret; Zucker, Marc; Lariviere, Doris
• Is Part Of: American journal of hospice & palliative care. Volume 30:Number 4(2013)
• Page Start: 403
• Page End: 405
• Publication Date: 2013-06
• Subjects: cisapride -- chronic intestinal pseudo-obstructions -- case report -- children -- feeding tolerance -- hospice and palliative care; Hospice care -- Periodicals; Palliative treatment -- Periodicals; 362.175
• DOI: 10.1177/1049909112457238
• Languages: English
• ISSNs: 1049-9091

Abstract

Cisapride is a gastrointestinal prokinetic that facilitates or restores motility along the entire gastrointestinal tract. It has been used successfully to treat acute and chronic intestinal pseudo-obstructions (CIPs) in adults, but there is a paucity of literature surrounding the treatment of CIP in pediatric patients and therapies for CIP are limited and their impact is often unsatisfactory. This case report presents the use of cisapride in the management of pseudo-obstruction. Treatment with cisapride substantially improved the patient's symptoms and improved feeding tolerance. It improved his prognosis remarkably and prevented the need for end-of-life care. He experienced no adverse effects throughout the course of therapy. The treatment regimen is discussed in this case report.