A Functional Assessment Tool to Distinguish Controls From Alzheimer's Disease in Lima, Peru. (16th May 2022)

• Record Type: Journal Article
• Authors: Custodio, Nilton; Montesinos, Rosa; Chambergo-Michilot, Diego; Herrera-Perez, Eder; Pintado-Caipa, Maritza; Seminario G, Wendy; Cuenca, José; Mesía, Laura; Failoc-Rojas, Virgilio E; Diaz, Monica M
• Is Part Of: American journal of Alzheimer's disease & other dementias. Volume 37(2022)
• Publication Date: 2022-05-16
• Subjects: alzheimer disease -- dementia -- neurocognitive disorders -- peru -- validation study; Alzheimer's disease -- Periodicals; Dementia -- Periodicals; Alzheimer's disease -- Patients -- Care -- United States -- Periodicals; 616.83
• DOI: 10.1177/15333175221104354
• Languages: English
• ISSNs: 1533-3175

Abstract

Background: The Alzheimer's Disease Cooperative Study-Activities of Daily Living (ADCS-ADL) scale is a versatile functional assessment tool for patients with Alzheimer's disease (ad ). We evaluated its performance in controls, Peruvians with MCI or AD. Methods: A cross-sectional study of older adults attending a neurology institute in Lima (Peru) with mild cognitive impairment (MCI), ad or cognitively healthy. Test-retest reliability (intraclass correlation coefficient, ICC; internal consistency, Cronbach's alpha) and validity were assessed. Results: We enrolled 276 individuals (ad : 113, MCI: 68, controls: 95) with no age, sex, educational level, and depressive symptom differences. Reliability was ideal (ICC: .996), and Cronbach's alpha was adequate (.937). The ADCS-ADL could not differentiate MCI from controls but did differentiatead severity. The ADCS-ADL correlated highly with nearly all tools. Conclusions: The ADCS-ADL scale is reliable in a population withad in Lima, Peru. Future work may validate a tool for Peruvians with lower educational levels.