Diabetes in Pregnancy Study Group India (DIPSI) and WHO (1999) diagnostic criteria for GDM: A meta-analysis. Issue 10 (October 2022)

• Record Type: Journal Article
• Authors: Rawat, Dimple; Zangmo, Rinchen; Chowdhury, Sumit Roy; Yadav, Arun Kumar; Sharma, K Aparna; Singh, Neeta; Pandey, Shivam
• Is Part Of: Diabetes & metabolic syndrome. Volume 16:Issue 10(2022)
• Publication Date: 2022-10
• Subjects: GDM -- DIPSI -- WHO-1999; Diabetes -- Periodicals; Metabolism -- Disorders -- Periodicals; Diabetes Mellitus -- Periodicals; Metabolic Diseases -- Periodicals; Diabète -- Périodiques; Métabolisme, Troubles du -- Périodiques; Endocrinologie -- Périodiques; Diabète -- Physiopathologie -- Périodiques; Diabetes; Metabolism -- Disorders; Electronic journals; Periodicals; 616.462
• DOI: 10.1016/j.dsx.2022.102622
• Languages: English
• ISSNs: 1871-4021

Abstract

Abstract: Background and aims: The diagnosis of Gestational diabetes mellitus (GDM) is challenging and controversial due to the heterogeneity or lack of consensus regarding the screening and diagnostic criteria for GDM. Methods: A meta-analysis of studies comparing Diabetes in Pregnancy Study Group India (DIPSI) and WHO 1999 for diagnosing GDM was carried out. Results: A total of 6 comparative studies were included. Pooled analysis showed sensitivity and specificity as 0.79 (95% CI: 0.53 to 0.92) and 0.97 (95% CI: 0.94 to 0.98) respectively. Conclusion: Based on the results of the meta-analysis, DIPSI showed higher specificity when compared to WHO 1999, hence may be used to rule in disease in probable GDM cases. However, the results should be interpreted more cautiously and carefully since only a few studies were included. Highlights: DIPSI showed higher specificity when compared to WHO 1999, as diagnostic criteria for GDM. Studies are required to compare diagnostic accuracy of DIPSI with respect to WHO 2013 criteria, to explore if DIPSI can be used in affluent settings. DIPSI can be used where logistic issues are a major concern and more research is required before we start using it for diagnostic purpose.