Successful desensitization after hypersensitivity reaction to cisplatin in a patient with nasopharyngeal carcinoma. Issue 10 (22nd October 2022)

• Record Type: Journal Article
• Authors: Kinouchi, Arisa; Ishii, Hiroki; Sakamoto, Kaname; Sakurai, Daiju
• Is Part Of: Clinical case reports. Volume 10:Issue 10(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-10-22
• Subjects: carboplatin -- cisplatin -- desensitization -- hypersensitivity reaction -- nasopharyngeal carcinoma; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.6444
• Languages: English
• ISSNs: 2050-0904

Abstract

Abstract: Hypersensitivity reaction to cisplatin can result in discontinuation of chemoradiotherapy in patients with head and neck squamous cell carcinoma. We describe a patient with nasopharyngeal carcinoma who developed cisplatin hypersensitivity and was successfully treated with cisplatin desensitization. Furthermore, it had little impact on the therapeutic performance of cisplatin‐combined chemoradiotherapy. Abstract : Cisplatin hypersensitivity can result in the discontinuation of chemoradiotherapy in patients with head and neck squamous cell carcinoma. Desensitization protocol had little impact on the therapeutic performance of cisplatin‐combined chemoradiotherapy.