Left atrial myocardial intrinsic function remodeling response to repair of primary mitral regurgitation. Issue 10 (8th September 2022)

• Record Type: Journal Article
• Authors: Lisi, Matteo; Cameli, Matteo; Mandoli, Giulia Elena; Pastore, Maria Concetta; Righini, Francesca Maria; Flamigni, Filippo; D'Ascenzi, Flavio; Cavigli, Luna; Focardi, Marta; Rubboli, Andrea; Campo, Gianluca; Mondillo, Sergio; Henein, Michael Y.
• Is Part Of: Echocardiography. Volume 39:Issue 10(2022)
• Page Start: 1264
• Page End: 1268
• Publication Date: 2022-09-08
• Subjects: echocardiography -- left atrial -- left ventricular -- mitral regurgitation -- remodeling; Echocardiography -- Periodicals; Echocardiography -- Periodicals; 616.1207543
• DOI: 10.1111/echo.15452
• Languages: English
• ISSNs: 0742-2822

Abstract

Abstract: Severe mitral regurgitation (MR) is a common valve disease which is associated with high mortality, if only managed medically. MR produces chronic and progressive volume overload with left atrial (LA) and left ventricular (LV) dilatation and dysfunction, atrial fibrillation (AF) and eventually myocardial fibrosis, irrespective of ejection fraction (EF). Surgical correction (mitral valve repair) of MR removes the volume overload, hence unmasks pre‐operative LV structure and function disturbances, including reduced EF and global longitudinal and circumferential strain, as well as LA volume and strain. This review aims at describing LA remodeling before and after surgical repair.