Esophageal submucosal tumor diagnosed with EBUS‐guided transbronchial mediastinal cryobiopsy: A case report. Issue 21 (13th September 2022)

• Record Type: Journal Article
• Authors: Ishiguro, Yuki; Uchimura, Keigo; Furuse, Hideaki; Imabayashi, Tatsuya; Matsumoto, Yuji; Watanabe, Shun‐Ichi; Tsuchida, Takaaki
• Is Part Of: Thoracic cancer. Volume 13:Issue 21(2022)
• Page Start: 3068
• Page End: 3072
• Publication Date: 2022-09-13
• Subjects: bronchoscopy -- cryobiopsy -- endobronchial ultrasound‐guided transbronchial needle aspiration -- esophageal neoplasms -- leiomyoma; Chest -- Cancer -- Periodicals; Chest -- Cancer -- Treatment -- Periodicals; Chest -- Surgery -- Periodicals; 616.99494005
• DOI: 10.1111/1759-7714.14650
• Languages: English
• ISSNs: 1759-7706

Abstract

Abstract: Cryobiopsy is advantageous for collecting larger specimens with minimum crushing compared to forceps biopsy and transbronchial needle aspiration (TBNA), but it has not been widely used for mediastinal tumors. In this report, a leiomyoma of the thoracic esophagus was diagnosed with endobronchial ultrasound‐guided transbronchial mediastinal cryobiopsy (EBUS‐cryo). An asymptomatic 49‐year‐old woman had a 2.6‐cm sized submucosal tumor (SMT) of the esophagus adjacent to the trachea and left main bronchus. EBUS‐TBNA and EBUS‐guided intranodal forceps biopsy were performed, followed by EBUS‐cryo. The biopsy forceps could not be inserted into the tumor, but the cryoprobe was smoothly inserted. EBUS‐TBNA could not obtain enough spindle‐shaped tumor cells for immunohistochemical staining, but EBUS‐cryo provided sufficient specimens for diagnosing the leiomyoma. Adding EBUS‐cryo to EBUS‐TBNA has recently been reported to achieve high diagnostic yields for lymphomas, uncommon tumors, and benign diseases. EBUS‐cryo seems a valid diagnostic option for esophageal SMTs that are difficult to diagnose with needles and forceps. Abstract : We present a case of leiomyoma of the thoracic esophagus diagnosed with endobronchial ultrasound‐guided transbronchial mediastinal cryobiopsy (EBUS‐cryo). Unlike endobronchial ultrasound‐guided transbronchial needle aspiration, EBUS‐cryo provided sufficient specimens for a leiomyoma diagnosis without serious complications. EBUS‐cryo is a valid option for esophageal submucosal tumors that are difficult to diagnose with needle and forceps biopsy.