Back Cover: On‐Site Non‐enzymatic Orthogonal Activation of a Catalytic DNA Circuit for Self‐Reinforced In Vivo MicroRNA Imaging (Angew. Chem. Int. Ed. 45/2022). Issue 45 (25th October 2022)

• Record Type: Journal Article
• Authors: He, Shizhen; Yu, Shanshan; Li, Ruomeng; Chen, Yingying; Wang, Qing; He, Yuqiu; Liu, Xiaoqing; Wang, Fuan
• Is Part Of: Angewandte Chemie international edition. Volume 61:Issue 45(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-10-25
• Subjects: DNA Circuit -- Fluorescence -- RNA -- Signal Amplification -- Tumor Imaging; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.202215016
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract : A non‐enzymatic circuitry activation strategy can realize an orthogonally controlled catalytic DNA (CCD) circuit through multiple molecular recognition events and progressively accelerated signal amplification, as reported by Fuan Wang and co‐workers in their Research Article (e202206529) . The on‐site activated CCD circuitry system has considerable potential for high‐precision in vivo imaging of low‐abundance microRNA.