CLINICAL CHARACTERISTICS OF STREAKY MULTIFOCAL CHOROIDITIS: A Subtype of Multifocal Choroiditis. Issue 11 (November 2022)

• Record Type: Journal Article
• Authors: Chen, Chunli; Cheng, Yizhe; Zhang, Zhihan; Zhang, Yongpeng; Xiao, Yuanyuan; Peng, Xiaoyan
• Is Part Of: Retina. Volume 42:Issue 11(2022)
• Page Start: 2110
• Page End: 2119
• Publication Date: 2022-11
• Subjects: multifocal choroiditis (MFC) -- linear streaks -- curvilinear streaks -- clinical characteristics -- multimodal imaging; Retina -- Diseases -- Periodicals; Retinal Diseases; Vitreous Body; 617.735
• DOI: 10.1097/IAE.0000000000003569
• Languages: English
• ISSNs: 0275-004X

Abstract

Abstract : This study is a retrospective case series to describe and analyze clinical characteristics of SMFC, as a subtype of MFC. Abstract : Purpose: To describe and analyze clinical characteristics of multifocal choroiditis with linear streaks (LSs). Methods: Eight cases of multifocal choroiditis with LSs were retrospectively studied. Multimodal imaging was performed. Demographic data and spherical equivalent were collected. Axial length was measured. Results: All cases are young myopic women with a mean age of 17.13 ± 3.64 years (range, 13–23 years), presenting with vision loss and distortion. Nine eyes with LSs were high myopia of −8.97 ± 2.69 D (range, −6.00 to 12.5 D; growing by 1.88 ± 0.61 D annually since wearing glasses), with mean axial length of 26.36 ± 1.71 mm. Vitreous cells were noted in seven eyes. LSs were located in the equator (eight eyes), around the optic disk (three eyes), and at the edge of the posterior pole (one eye). Angio-optical coherence tomography showed choroidal neovascularization in eight eyes, especially 2 to 3 choroidal neovascularizations in three eyes. The location of choroidal neovascularization were in subfovea (three eyes), parafovea (six eyes), and perifovea (two eyes). Swept source optical coherence tomography showed punched-out disruption of retinal pigment epithelium‒Bruch's membrane‒choriocapillaris complex at the LSs' sites. LSs showed fluorescence staining on late FA but hypofluorescence throughout all phases on ICGA. Conclusion: Multifocal choroiditis with LSs mostly occurs in young women with high myopia, especially occurring in eyes with rapid progression of myopia. LSs are mainly located in the midperiphery near the equator, being prone to concur with choroidal neovascularization. Based on our findings, we propose a new term called "streaky multifocal choroiditis" as a subtype of multifocal choroiditis.