Manganese Catalyzed Hydrogenation of Azo (N=N) Bonds to Amines. Issue 15 (2nd July 2021)

• Record Type: Journal Article
• Authors: Das, Uttam Kumar; Kar, Sayan; Ben‐David, Yehoshoa; Diskin‐Posner, Yael; Milstein, David
• Is Part Of: Advanced synthesis & catalysis. Volume 363:Issue 15(2021)
• Page Start: 3744
• Page End: 3749
• Publication Date: 2021-07-02
• Subjects: Manganese -- Catalytic hydrogenation -- Azo (N=N) bond -- Amines -- Ligand metal cooperation; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202100440
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: We report the first example of homogeneously catalyzed hydrogenation of the N=N bond of azo compounds using a complex of an earth‐abundant‐metal. The hydrogenation reaction is catalyzed by a manganese pincer complex, proceeds under mild conditions, and yields amines, which makes this methodology a sustainable alternative route for the conversion of azo compounds. A plausible mechanism involving metal‐ligand cooperation and hydrazine intermediacy is proposed based on mechanistic studies. Abstract :