Inside Cover: Implications of Quenching‐to‐Dequenching Switch in Quantitative Cell Uptake and Biodistribution of Dye‐Labeled Nanoparticles (Angew. Chem. Int. Ed. 28/2021). Issue 28 (17th May 2021)

• Record Type: Journal Article
• Authors: Yang, Guangze; Liu, Yun; Hui, Yue; Tengjisi, ; Chen, Dong; Weitz, David A.; Zhao, Chun‐Xia
• Is Part Of: Angewandte Chemie international edition. Volume 60:Issue 28(2021)
• Page Start: 15114
• Page End: 15114
• Publication Date: 2021-05-17
• Subjects: biodistribution -- cell uptake -- fluorescence -- nanoparticles -- quenching; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.202105984
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract : A quenching‐to‐dequenching switch of fluorescence‐labeled nanoparticles in biological environments is unveiled by Chun‐Xia Zhao and co‐workers in their Research Article on page 15426 . With dye molecules in a solid state, the release and/or degradation of the dye‐labeled nanoparticles in biological environments led to a several‐fold increase in fluorescence intensity due to the state switch, which has significant implications in quantitative cell uptake and biodistribution studies.