PIN-A1, a novel Casein Kinase 1α-selective molecular glue degrader, demonstrates strong antitumor activity via activation of the p53 pathway in preclinical models of AML with a favorable safety profile. (October 2022) - Jung, J.; Park, J.; Mohanty, S.; Kim, Y.; Levy, D.; King-Underwood, J.; Deninno, M.; Baek, J.; Choi, W.; Lee, S.; Lee, D.; Kang, H.; et al.