Advances in layered double hydroxide based labels for signal amplification in ultrasensitive electrochemical and optical affinity biosensors of glucose. (December 2022)

• Record Type: Journal Article
• Authors: Sohrabi, Hessamaddin; Dezhakam, Ehsan; Nozohouri, Ehsan; Majidi, Mir Reza; Orooji, Yasin; Yoon, Yeojoon; Khataee, Alireza
• Is Part Of: Chemosphere. Volume 309:Part 1(2022)
• Publication Date: 2022-12
• Subjects: Glucose -- Layered double hydroxide -- Electrochemical sensing platform -- Optical assay -- Biosensor; Pollution -- Periodicals; Pollution -- Physiological effect -- Periodicals; Environmental sciences -- Periodicals; Atmospheric chemistry -- Periodicals; 551.511
• DOI: 10.1016/j.chemosphere.2022.136633
• Languages: English
• ISSNs: 0045-6535

Abstract

Abstract: Since the development of enzyme electrodes, the research area of glucose biosensing has seen outstanding progress and improvement. Numerous sensing platforms have been developed based on different immobilization techniques and improved electron transfer between the enzyme and electrode. Interestingly, these platforms have consistently used innovative nanostructures and nanocomposites. In recent years, layered double hydroxides (LDHs) have become key tools in the field of analytical chemistry owing to their outstanding features and benefits, such as facile synthesis, cost-effectiveness, substantial surface area, excellent catalytic performance, and biocompatibility. LDHs are often synthesized as nanomaterial composites or manufactured with specific three-dimensional structures. The purpose of this review is to illustrate the biosensing prospects of LDH-based glucose sensors and the need for improvement. First, various clinical and conventional approaches for glucose determination are discussed. The definitions, types, and various synthetic methodologies of LDHs are then explained. Subsequently, we discuss the various research studies regarding LDH-based electrochemical and optical assays, focusing on modified systems, improved electron transfers pathways (through developments in surface science), and different sensing designs based on nanomaterials. Finally, a summary of the current limitations and future challenges in glucose analysis is described, which may facilitate further development and applications. Graphical abstract: Image 1 Highlights: The area of glucose biosensing has demonstrated outstanding growth and development. Nanoparticles have been utilized as components of a biosensor regarding glucose. LDHs have drawn an attention in analytical chemistry owing to their outstanding features. Definitions, types, and various synthesis methodologies of LDHs are explained. The review aims to recapitulate the evolution of the LDH-based glucose sensors.