Validity and reliability of CVI Range assessment for Clinical Research (CVI Range-CR): a longitudinal cohort study. Issue 1 (31st October 2022)

• Record Type: Journal Article
• Authors: Chang, Melinda; Roman-Lantzy, Christine; O'Neil, Sharon H; Reid, Mark W; Borchert, Mark S
• Is Part Of: BMJ open ophthalmology. Volume 7:Issue 1(2022)
• Publication Date: 2022-10-31
• Subjects: Visual (cerebral) Cortex -- Visual pathway; Ophthalmology -- Periodicals; 617.7005
• DOI: 10.1136/bmjophth-2022-001144
• Languages: English
• ISSNs: 2397-3269

Abstract

Abstract : Introduction: Cortical visual impairment (CVI) is the leading cause of paediatric visual impairment in developed countries. Children with CVI exhibit visual behaviours that differ from those with ocular causes of visual impairment. Currently, there is no standard method of assessing these visual characteristics. We have developed a modified version of the CVI Range, a functional vision assessment, suitable for use in clinical research (CVI Range–Clinical Research (CVI Range-CR)). The purpose of this study is to assess the reliability and validity of this instrument in children with CVI. Methods and analysis: This is a prospective cohort study of 45 children with CVI. A neuro-ophthalmologist will grade visual acuity using the six-level Visual Behaviour Scale (VBS). A neuropsychologist will administer the CVI Range-CR, which will be recorded. The neuropsychologist and two external graders will review and score recorded assessments. These procedures will be performed at baseline and 12 months. We will calculate the intraclass correlation coefficient to assess inter-rater reliability at baseline and follow-up. Additionally, we will correlate CVI Range-CR scores to VBS scores.