The first case of meningitis associated with SARS-CoV-2 BA.2 variant infection with persistent viremia. (November 2022)

• Record Type: Journal Article
• Authors: D'Abramo, Alessandra; Vita, Serena; Colavita, Francesca; Cimini, Eleonora; Haggiag, Shalom; Maffongelli, Gaetano; Valli, Maria Beatrice; Bevilacqua, Nazario; Corpolongo, Angela; Giancola, Maria Letizia; Maggi, Fabrizio; Agrati, Chiara; Nicastri, Emanuele
• Is Part Of: International journal of infectious diseases. Volume 124(2022)
• Page Start: 38
• Page End: 40
• Publication Date: 2022-11
• Subjects: COVID-19 -- Meningitis -- Omicron -- Blood barrier damage; Communicable diseases -- Periodicals; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; Electronic journals; 616.9
• DOI: 10.1016/j.ijid.2022.09.011
• Languages: English
• ISSNs: 1201-9712

Abstract

Highlights: Neurological disorders during COVID-19 are rare. Plasmatic viremia could be persistent in patients who are immunocompromised. Immunosuppression and blood-brain barrier injury could facilitate SARS-CoV-2 entry. Central nervous system SARS-CoV-2 detection should be performed in neurological patients. Abstract: Severe neurological disorders and vascular events during COVID-19 have been described. Here, we describe the first case of a female patient infected with the SARS-CoV-2 BA.2 Omicron variant of concern with meningitis with newly diagnosed central demyelinating disease.