Severe community-acquired pneumonia caused by Chlamydia pecorum. (November 2022)

• Record Type: Journal Article
• Authors: Cao, Lizhen; He, Lin; Wang, Siyuan; Xu, Lianjie; Zhuang, Shifang
• Is Part Of: International journal of infectious diseases. Volume 124(2022)
• Page Start: 171
• Page End: 173
• Publication Date: 2022-11
• Subjects: Chlamydia pecorum -- Community-acquired pneumonia -- Zoonosis -- mNGS; Communicable diseases -- Periodicals; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; Electronic journals; 616.9
• DOI: 10.1016/j.ijid.2022.09.037
• Languages: English
• ISSNs: 1201-9712

Abstract

HIGHLIGHTS: We report the first case of human Chlamydia pecorum pneumonia . C. pecorum infection was identified by metagenomic next-generation sequencing and complement fixation test. The patient was a farmer with diabetes and had close contact with sheep. High fever, dry cough, and pulmonary consolidation are the main features. Abstract: Chlamydia pecorum is a zoonotic pathogen. Here, we report the first case of human infection with C. pecorum . A man aged 51 years with high fever and dry cough was diagnosed with severe community-acquired pneumonia and respiratory failure. C. pecorum was found responsible for the infection, which was detected from bronchoalveolar lavage fluid through metagenomic next-generation sequencing. C. pecorum infection was further identified by quantitative polymerase chain reaction and complement fixation test. The patient's condition improved rapidly after targeted treatment. He was a farmer with diabetes mellitus and had a history of close contact with sheep, which might result in C. pecorum infection. Our report could provide a direction for the diagnosis and treatment of human C. pecorum pneumonia .