Recent advancements in astaxanthin production from microalgae: A review. (November 2022)

• Record Type: Journal Article
• Authors: Patel, Anil Kumar; Tambat, Vaibhav Sunil; Chen, Chiu-Wen; Chauhan, Ajeet Singh; Kumar, Prashant; Vadrale, Akash Pralhad; Huang, Chun-Yung; Dong, Cheng-Di; Singhania, Reeta Rani
• Is Part Of: Bioresource technology. Volume 364(2022)
• Publication Date: 2022-11
• Subjects: Astaxanthin -- Microalgae -- Carotenoid -- Antioxidant -- Pigment; Biomass -- Periodicals; Biomass energy -- Periodicals; Bioremediation -- Periodicals; Agricultural wastes -- Periodicals; Factory and trade waste -- Periodicals; Organic wastes -- Periodicals; Bioénergie -- Périodiques; Déchets agricoles -- Périodiques; Déchets industriels -- Périodiques; Déchets organiques -- Périodiques; Déchets (Combustible) -- Périodiques; 662.88
• DOI: 10.1016/j.biortech.2022.128030
• Languages: English
• ISSNs: 0960-8524

Abstract

Graphical abstract: Highlights: Microalgal astaxanthin is a super antioxidant molecule used as dietary supplements. It possesses multifold bioactivities than other carotenoids/artificial astaxanthin. Microalgal carotenoid market is expected to reach million ∼$550 by the year 2025. Microalgal carotenoids exhibit 2–10 folds higher bioactivity than synthetic pigments. Abstract: Microalgae have emerged as the best source of high-value astaxanthin producers. Algal astaxanthin possesses numerous bioactivities hence the rising demand for several health applications and is broadly used in pharmaceuticals, aquaculture, health foods, cosmetics, etc. Among several low-priced synthetic astaxanthin, natural astaxanthin is still irreplaceable for human consumption and food-additive uses. This review highlights the recent development in production enhancement and cost-effective extraction techniques that may apply to large-scale astaxanthin biorefinery. Primarily, the biosynthetic pathway of astaxanthin is elaborated with the key enzymes involved in the metabolic process. Moreover, discussed the latest astaxanthin enhancement strategies mainly including chemicals as product inducers and byproducts inhibitors. Later, various physical, chemical, and biological cell disruption methods are compared for cell disruption efficiency, and astaxanthin extractability. The aim of this review is to provide a comprehensive review of advancements in astaxanthin research covering scalable upstream and downstream astaxanthin bioproduction aspects.