Necrotizing fasciitis associated with malignancy. Issue 2 (February 2020)

• Record Type: Journal Article
• Authors: Chen, Leon L.; Tayban, Kate; Caravanos, Christopher; Shaz, David; Halpern, Neil A.
• Is Part Of: Journal of the American Association of Nurse Practitioners. Volume 32:Issue 2(2020)
• Page Start: 109
• Page End: 112
• Publication Date: 2020-02
• Subjects: Clostridium septicum -- multiorgan failure -- necrotizing fasciitis -- septic shock; Nurse practitioners -- Periodicals; Nursing -- Periodicals; 610.730692
• DOI: 10.1097/JXX.0000000000000251
• Languages: English
• ISSNs: 2327-6886

Abstract

ABSTRACT: Necrotizing fasciitis (NF) is a rare soft-tissue condition with a high mortality rate even with treatment. Diagnosis is challenging due to an absence of specific symptoms at the early stages of clinical presentation. NF is typically associated with traumatic injuries, superficial skin breakdown, and surgical procedures. Diabetes mellitus and immunosuppression also increase the risk of developing NF. NF predominantly occurs in the lower extremities, the peritoneum, and the perineum. Treatments include antimicrobials, supportive care, and surgical source control. It is important for clinicians to recognize the association of spontaneous atraumatic NF caused by Clostridium septicum with malignancy, so they can maintain a high index of suspicion and provide timely interventions to optimize patient outcomes.