Long-standing Multifocal Motor Neuropathy Presenting With Delayed Clinical Features of Anti–Myelin-Associated Glycoprotein Neuropathy and Elevated Anti–Myelin-Associated Glycoprotein Antibody Titers. Issue 3 (March 2021)

• Record Type: Journal Article
• Authors: Bernardo, Katrina A.; Weiss, Michael D.
• Is Part Of: Journal of clinical neuromuscular disease. Volume 22:Issue 3(2021:Mar.)
• Page Start: 169
• Page End: 172
• Publication Date: 2021-03
• Subjects: anti-MAG neuropathy -- multifocal motor neuropathy -- coexistence -- nerve conduction study; Neuromuscular diseases -- Periodicals; 616.744005
• DOI: 10.1097/CND.0000000000000334
• Languages: English
• ISSNs: 1522-0443

Abstract

Abstract: Multifocal motor neuropathy with conduction block (MMN) and anti–myelin-associated glycoprotein (MAG) neuropathy are rare chronic acquired demyelinating neuropathies with distinct clinical and electrophysiological characteristics. These neuropathies are generally not known to coexist. This report describes a patient with long-standing MMN who subsequently developed clinical features of anti-MAG neuropathy. This suggests that subtypes of chronic inflammatory neuropathies may not be sharply defined. In addition, a presentation of MMN with anti-MAG titers may be a prognostic indicator of poor response to standard MMN treatment.