A Case of Profound Secretory Diarrhea Revealing 2 Primary Neuroendocrine Tumors. Issue 7 (8th July 2021)

• Record Type: Journal Article
• Authors: Thompson, Ashley A.; Suhail, Fathima K.; Mirchia, Kanish; Rawlins, Sekou R.
• Is Part Of: ACG Case Reports Journal. Volume 8:Issue 7(2021)
• Page Start: e00625
• Publication Date: 2021-07-08
• DOI: 10.14309/crj.0000000000000625
• Languages: English
• ISSNs: 2326-3253

Abstract

ABSTRACT: Neuroendocrine tumors (NETs) are unusual neoplasms with a diverse spectrum of clinical presentations. There is a lack of literature on cases of 2 primary histologically distinct NETs. We report a case of a 40-year-old man who presented with chronic diarrhea. A colonoscopy was performed which discovered a rectal polyp, with pathology showing a well-differentiated NET. A subsequent somatostatin scan revealed a pancreatic tail mass. Biopsy showed a histologically distinct well-differentiated vasoactive intestinal peptide-producing NET. Given that pancreatic and rectal NETs come from different embryonic origins, the diagnosis of 2 primary NETs presents a unique case.