Current Challenges in Fecal Microbiota Transplantation for Clostridioides difficile Infection in Children. (18th September 2021)

• Record Type: Journal Article
• Authors: Nicholson, Maribeth R.; Hourigan, Suchitra K.; Conrad, Maire; Goyal, Alka; Jensen, Kyle; Kelsen, Judith; Kennedy, Melissa; Weatherly, Madison; Kahn, Stacy A.
• Is Part Of: American journal of gastroenterology. Volume 116:Number 9(2021)
• Page Start: 1954
• Page End: 1956
• Publication Date: 2021-09-18
• Subjects: Stomach -- Diseases -- Periodicals; Intestines -- Diseases -- Periodicals; Gastroenterology -- Periodicals; Gastrointestinal Diseases -- Periodicals; Electronic journals; Periodicals; 616.33
• DOI: 10.14309/ajg.0000000000001350
• Languages: English
• ISSNs: 0002-9270

Abstract

Abstract : INTRODUCTION: The impact of the 2019 US Food and Drug Administration safety alert involving transmission of multidrug resistant organisms through fecal microbiota transplantation (FMT), and the COVID-19 pandemic on the use of FMT in children, is unknown. METHODS: A survey of pediatric gastroenterologists performing FMT for Clostridioides difficile infection was conducted. RESULTS: Of 36 respondents, 17 (47%) and 30 (83%) changed their FMT practices related to the US Food and Drug Administration safety alert and COVID-19 pandemic, respectively, with 22 (61%) of programs halted. DISCUSSION: The US Food and Drug Administration safety alert and COVID-19 pandemic have substantially influenced the availability and access of FMT for children.