Boosting the Selective Electrochemical Signals for Simultaneous Determination of Chloramphenicol and Furazolidone in Food Samples by Using ZnFe2O4-Based Sensing Platform: Correlation between Analyte Molecular Structure and Electronic Property of Electrode Materials. Issue 10 (1st October 2022)

• Record Type: Journal Article
• Authors: Huyen, Nguyen Ngoc; Anh, Nguyen Tuan; Phung, Thi Lan Huong; Dinh, Ngo Xuan; Vinh, Nguyen Thanh; Loan, To Thanh; Nguyen, Van Quy; Vu, Dinh Lam; Tung, Le Minh; Le, Anh-Tuan
• Is Part Of: Journal of the Electrochemical Society. Volume 169:Issue 10(2022)
• Publication Date: 2022-10-01
• Subjects: Zinc Ferrite (ZnFe2O4) -- Zinc oxide (ZnO) -- Chloramphenicol -- Furazolidone -- electrochemical sensor; Electrochemistry -- Periodicals; 541.3705
• DOI: 10.1149/1945-7111/ac9715
• Languages: English
• ISSNs: 0013-4651

Abstract

Abstract : In this study, ZnFe2 O4 -based nanostructures, including ZnFe2 O4 nanoparticles and ZnFe2 O4 /ZnO nanocomposite, were introduced on screen-printed electrodes surface (SPEs) for enhancing the selective electrochemical signals towards the chloramphenicol (CAP) and furazolidone (FZD) antibiotics. The difference in the molecular structure of CAP and FZD leads to significant changes in adsorption capacity and electron transfer kinetic at modified electrodes. Interestingly, FZD antibiotic with formal reduction potential (E0 ') near the Fermi level of ZnFe2 O4 -based nanostructures showed a strong dependence of electrochemical response with electron transfer kinetic. In contrast, CAP antibiotic with E0 ' away from the Fermi level of ZnFe2 O4 -based nanostructures showed the high sensitivity of electrochemical response with the electroactive surface area of modified electrodes. The obtained results might offer the basis to develop a suitable approach for improving the analytical performance of advanced spinel oxide nanostructures-based electrochemical sensing devices. Under optimal conditions, ZnFe2 O4 /ZnO/SPEs enabled the simultaneous monitoring of CAP and FZD in the linear working ranges of 0.5–100 μ M and 0.5–75 μ M with high electrochemical sensitivity of 1.87 and 1.82 μ A μ M −1 cm −2, respectively. The ZnFe2 O4 -based electrochemical nanosensor exhibited high repeatability and long-term storage stability for simultaneous analysis of CAP and FZD in milk sample.