Snakebite incidence in rural sub-Saharan Africa might be severely underestimated. (November 2022)

• Record Type: Journal Article
• Authors: Farooq, Harith; Bero, Cláudio; Guilengue, Yolanda; Elias, Clementina; Massingue, Yasalde; Mucopote, Ivo; Nanvonamuquitxo, Cristóvão; Marais, Johan; Faurby, Søren; Antonelli, Alexandre
• Is Part Of: Toxicon. Volume 219(2022)
• Publication Date: 2022-11
• Subjects: Africa -- Households -- Mozambique -- Snakebite -- Snakes -- Survey -- Traditional medicine; Toxins -- Periodicals; Venom -- Periodicals; 615.9
• DOI: 10.1016/j.toxicon.2022.106932
• Languages: English
• ISSNs: 0041-0101

Abstract

Abstract: Snakebites in sub-Saharan Africa account for 20, 000 to 32, 000 annual deaths. But since most data is retrieved from hospital or incomplete central databases, and many victims do not seek hospital treatment or prefer traditional remedies, the current numbers are likely underestimated. In order to reduce snakebite incidence by 50% by 2030 as targeted by World Health Organization, it is crucial to accurately quantify and understand the current rates of snakebite incidence, which can only be reliably measured through household surveys. In this study, we interviewed 1037 households in nine communities in Cabo Delgado, northern Mozambique. Our aim was to quantify true snakebite incidence and under-reporting, by comparing the total number of snakebites reported to our team during household surveys with the subset of reports that reached health centers. We additionally quantified snakebite incidence in terms of species, location of the attack, type of treatment, season, and gender of the victims. These data allow us to propose conservative extrapolations of snakebite incidence and mortality for the province of Cabo Delgado and for Mozambique. Of all snakebites reported in the surveys (N = 296), most incidents were treated exclusively by traditional doctors (N = 174; 59%) and 25% were not seen by any doctor. Most bites occurred on farms and during the rainy season. Using a conservative estimation where we assume our results to be extrapolatable for the whole of rural Mozambique, but considering snakebites in urban areas to be inexistent, we propose that in Cabo Delgado, every year at least 6124 people are victims of snakebites, of which at least 791 result in deaths. In Mozambique, we extrapolated that every year at least 69, 261 people are victims of snakebite, of which at least 8950 result in death (one in eight snakebites is fatal). Our estimates are the first for Mozambique based on data retrieved in the country, and despite being an underestimation they increase snakebite incidence levels ten-fold and the number of deaths by 30-fold. Urgent and widespread surveys are needed to further assess the full extent of snakebites in sub-Saharan Africa, explore regional patterns and develop mitigation plans. Graphical abstract: Image 1 Highlights: We gathered snakebite data from 1037 households in 9 communities in northern Mozambique. 59% of snakebites are treated exclusively by traditional doctors and 25% are not seen by any doctor. In Mozambique, every year 69, 261 people are victims of snakebite. One in eight snakebites in Mozambique results in death. Our estimates, increase snakebite incidence levels ten-fold and deaths by 30-fold.