Efficacy and safety of cold snare polypectomy for sessile serrated polyps ≥ 10 mm: A systematic review and meta-analysis. Issue 11 (November 2022)

• Record Type: Journal Article
• Authors: Li, De-feng; Van Overbeke, Lode; Ohata, Ken; Wang, Li-sheng; Yao, Jun
• Is Part Of: Digestive and liver disease. Volume 54:Issue 11(2022)
• Page Start: 1486
• Page End: 1493
• Publication Date: 2022-11
• Subjects: Cold snare polypectomy -- Sessile serrated adenomas/polyps -- Meta-analysis; CSP cold snare polypectomy -- SSPs sessile serrated polyps -- AEs adverse events -- EMR endoscopic mucosal resection -- ESD endoscopic submucosal dissection -- PEB post-EMR bleeding -- DMI deep mural injury -- PPB post-procedure bleeding -- PRISMA Preferred Reporting Items for Systematic Reviews and Meta-Analysis -- NOS Newcastle-Ottawa Scale; Digestive organs -- Diseases -- Periodicals; Liver -- Diseases -- Periodicals; 616.33005
• DOI: 10.1016/j.dld.2022.01.132
• Languages: English
• ISSNs: 1590-8658

Abstract

Abstract: Background: Cold snare polypectomy (CSP) is a promising technique for the removal of sessile serrated polyps (SSPs) ≥ 10 mm. However, the efficacy and safety of this technique remain undetermined. Aims: We aimed to comprehensively evaluate the efficacy and safety of CSP for SSPs ≥ 10 mm. Methods: PubMed, EMBASE, Web of Science and Cochrane Library were searched up to January 2021. Results: A total of 10 studies consisting of 1727 SSPs (range, 10–40 mm) from 1021 patients were included. The overall rates of technical success, adverse events (AEs) and residual SSPs were 100%, 0.7% and 2.9%, respectively. Subgroup analysis showed that the rates of technical success and AEs were comparable between CSP and cold endoscopic mucosal resection (EMR) (99.9% vs. 100% and 1.3% vs. 0.5%, respectively), between the proximal and distal colon (100% vs. 99.9% and 0.3% vs. 0, respectively), and between polyps of 10–19 mm and ≥20 mm (99.8% vs. 100% and 0.9% vs. 0, respectively). However, subgroup analysis showed that the rate of residual SSPs was slightly lower in CSP compared with cold EMR (1.3% vs. 3.9%), as well as in polyps of 10–19 mm compared with those ≥20 mm (3.1% vs. 4.7%). Conclusion: CSP was an effective and safe technique for removing SSPs ≥ 10 mm.