Performance metrics of AI-enhanced single lead EKG maintained after entry of organised clustered data. (3rd October 2022)

• Record Type: Journal Article
• Authors: Mehta, S; Vieira, D; Zerpa, D; Guillen, V; Gonzalez, A; Brena-Pastor, L; Siyam, T; Stoica, S; Ozair, S; Pinos, D; Martinez, F; Fleming, M; Carrera, K; Rossitto, F; Whuking, C
• Is Part Of: European heart journal. Volume 43(2022)Supplement 2
• Publication Date: 2022-10-03
• Subjects: Cardiology -- Periodicals; Heart -- Diseases -- Periodicals; 616.12005
• DOI: 10.1093/eurheartj/ehac544.2786
• Languages: English
• ISSNs: 0195-668X

Abstract

Abstract: Background: Our experience in creating innovative Artificial Intelligence-guided single lead EKG methodologies for ST-Elevation Myocardial Infarction (STEMI) detection within complex EKG records has been previously validated. Purpose: By expanding the intricate variables of our previously tested algorithm input, we seek to further improve our STEMI detecting tool. Methods: 11, 567 12-lead EKG records (10-s length, 500 Hz sample frequency) derived from the Latin America Telemedicine Infarct Network database from April 2014 to December 2019. From these records, we included the following balanced classes: angiographically confirmed and unconfirmed STEMI (divided by wall affected), branch blocks, non-specific ST-T changes, normal, and abnormal (Remaining 200+ CPT codes). Cardiologist annotations ensured precision (Ground truth). Determined classes were "STEMI" and "Not-STEMI". A 1-D Convolutional Neural Network model was trained and tested for each lead with dataset proportions of 90/10, respectively. The last dense layer outputs a probability for each record being STEMI/Not-STEMI. The analysis also included performance metrics and false-negative reports. Results: Overall, the most promising Single lead for STEMI detection was V2 (91.2% Accuracy, 89.6% Sensitivity, and 92.9% Specificity). 55% of false negatives were inferior wall STEMI (Table 1). Conclusion: Appreciable progress of our new methodology compared to our previous experiences in AI-guided Single Lead for STEMI detection, especially for lead V2. By performing a thorough analysis of false-negative reports, we aspire to identify potential areas of STEMI detection weakness which will become the focus of future ventures. Funding Acknowledgement: Type of funding sources: None.