Duodenal gastrointestinal stromal tumor: A case report. (October 2022)

• Record Type: Journal Article
• Authors: Yadav, Saroj Kumar; Bhattarai, Himal Bikram; Rijal, Ashes; Shrestha, Anish; Shah, Sangam; Subedi, Ayusha; Yadav, Binita Kumari; Acharya, Aakash; Khatri, Rojee; Kadel, Gareema
• Is Part Of: Annals of medicine and surgery. Volume 82(2022)
• Publication Date: 2022-10
• Subjects: Duodenal GIST -- GI bleed -- Imatinib; Surgery -- Periodicals; Medicine -- Periodicals; General Surgery -- Periodicals; Education, Medical -- Periodicals; Periodicals; 617
• DOI: 10.1016/j.amsu.2022.104574
• Languages: English
• ISSNs: 2049-0801

Abstract

Abstract: Introduction: Gastrointestinal tumor (GIT) is an uncommon gastrointestinal tumor most commonly arising in the stomach. Duodenum is an uncommon site accounting for only about 3–5% of cases. Case presentation: In this case report, we present a case of high-risk duodenal GIST and review its management strategies. Discussion: An abdominal mass and gastrointestinal (GI) bleeding are its usual presentation, however it may be lost among the long list of differentials of an abdominal mass and GI bleeding, if a high index of suspicion is not maintained. Surgery, with or without tyrosine kinase inhibitors like imatinib mesylate, has been the cornerstone in management of GIST. Conclusion: This case underlined the importance of duodenal GIST as a cause of GI bleed and abdominal mass as well as shone light upon historical developments, current updates and managements of GISTs. Highlights: Gastrointestinal tumor (GIT) is an uncommon gastrointestinal tumor most commonly arising in the stomach. Duodenal GIST as a cause of GI bleed and abdominal mass. Surgery, with or without tyrosine kinase inhibitors like imatinib mesylate, has been the cornerstone in management of GIST. Here, we presented a rare case of duodenal GIST which should be considered a differential when considering etiologies for GI bleed.