Parameters of high-frequency jet ventilation using a mechanical lung model. (3rd October 2022)

• Record Type: Journal Article
• Authors: Kukuev, Evgeni; Belugin, Evgeny; Willner, Dafna; Ronen, Ohad
• Is Part Of: Journal of medical engineering & technology. Volume 46:Number 7(2022)
• Page Start: 617
• Page End: 623
• Publication Date: 2022-10-03
• Subjects: High-frequency jet ventilation -- tidal volume -- minute volume -- respiratory rate -- inspiratory to expiratory ratio -- lung compliance -- lung model; Biomedical engineering -- Periodicals; Medical technology -- Periodicals; 610.28
• DOI: 10.1080/03091902.2022.2081370
• Languages: English
• ISSNs: 0309-1902

Abstract

Abstract: High frequency jet ventilationis a mechanical lung ventilation method which uses a relatively high flow usually through an open system. This work examined the effect of high-frequency jet ventilation on respiratory parameters of an intubated patient simulated using a high-frequency jet ventilator attached to a ventilation monitor for measurements of ventilation parameters. The series of experiments altered specific parameters each time (respiratory rate, inspiratory-expiratory (I:E) ratio, and inspiratory pressure), under different lung compliances. A reduction of minute ventilation was observed alongside a rise in respiratory rate, with low airway pressures over the entire range of lung compliances. In addition, an I:E ratio of 2:1 to 1:1; and the tidal and minute volumes were directly related to the inspiratory pressure over all compliance settings. To conclude, the respiratory mechanics in high-frequency jet ventilation are very different from those of conventional rate ventilation in a lung model. Further studies on patients and/or a biological model are needed to investigate pCO2 and end-tidal carbon-dioxide during high-frequency jet ventilation.