Recent advances in the cascade reactions of enynols/diynols for the synthesis of carbo- and heterocycles. Issue 20 (15th September 2022)

• Record Type: Journal Article
• Authors: Jiang, Shimin; Ma, Haojie; Yang, Ruchun; Song, Xian-Rong; Xiao, Qiang
• Is Part Of: Organic chemistry frontiers. Volume 9:Issue 20(2022)
• Page Start: 5643
• Page End: 5674
• Publication Date: 2022-09-15
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d2qo01154a
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : This review summaries a view of the advances in the cascade reactions of enynols/diynols for the construction of carbo- and heterocycles. Abstract : Carbo- and heterocycles frequently serve as crucial scaffolds in drugs, natural products, fine chemicals, and biologically and pharmaceutically active compounds. Consequently, the development of general, practical, and efficient synthetic approaches for their preparation has attracted considerable attention from organic chemists. In the past few decades, the cascade cyclization of enynols and diynols has become a powerful tool to construct various frameworks. In this review, we highlight recent advances in this field toward the efficient construction of carbo- and heterocycles. According to the type of substrates, these transformations can be divided into two categories: (1) cascade reactions of enynols for the synthesis of carbo- and heterocycles; and (2) cascade reactions of diynols for the synthesis of carbo- and heterocycles.