Catalyst-free benzylic C(sp3)–H cross-coupling with organotrifluoroborates enabled by electrochemistry. Issue 20 (27th September 2022)

• Record Type: Journal Article
• Authors: Li, Chao; Ding, Ran; Guo, Heng-Yi; Xia, Shuang; Shu, Lei; Wang, Pei-Long; Li, Hongji
• Is Part Of: Green chemistry. Volume 24:Issue 20(2022)
• Page Start: 7883
• Page End: 7888
• Publication Date: 2022-09-27
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/d2gc02204d
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : An electrochemical benzylic C(sp 3 )–H cross-coupling with organotrifluoroborates without any catalyst or external electrolyte has been developed. Abstract : Herein, we report a rare catalyst-free electrochemical cross-coupling of benzylic C–H bonds with organotrifluoroborates, which readily proceeds at room temperature and provides a unique protocol for forging C(sp 3 )–C(sp 3 ), C(sp 3 )–C(sp 2 ) and C(sp 3 )–C(sp) bonds. In particular, this work discloses the dual role of organotrifluoroborates serving both as a coupling partner and an electrolyte in C(sp 3 )–H functionalization.