The development of disposable electrochemical sensor based on MoSe2-rGO nanocomposite modified screen printed carbon electrode for amitriptyline determination in the presence of carbamazepine, application in biological and water samples. (December 2022)

• Record Type: Journal Article
• Authors: Hasanpour, Matineh; Pardakhty, Abbas; Tajik, Somayeh
• Is Part Of: Chemosphere. Volume 308:Part 2(2022)
• Publication Date: 2022-12
• Subjects: Screen-printed carbon electrode -- MoSe2/Reduced graphene oxide nanocomposite -- Amitriptyline -- Carbamazepine; Pollution -- Periodicals; Pollution -- Physiological effect -- Periodicals; Environmental sciences -- Periodicals; Atmospheric chemistry -- Periodicals; 551.511
• DOI: 10.1016/j.chemosphere.2022.136336
• Languages: English
• ISSNs: 0045-6535

Abstract

Abstract: The present attempt developed a simple sensing system based on the modification of screen-printed carbon electrode (SPCE) with MoSe2 /reduced graphene oxide (rGO) nanocomposite (MoSe2 -rGO/SPCE) to voltammetrically co-detect amitriptyline and carbamazepine. Different techniques such as field emission scanning electron microscopy (FE-SEM), energy dispersive X-ray (EDX), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR) were employed to characterize MoSe2 -rGO nanocomposite morphology and structure. Moreover, chronoamperometry, differential pulse voltammetry (DPV) and linear sweep voltammetry (LSV) were utilized to explore the electrochemical oxidation of amitriptyline. Data revealed a great current sensitivity for the MoSe2 -rGO/SPCE towards amitriptyline. The peak currents of amitriptyline oxidation on the MoSe2 -rGO/SPCE had linear dynamic range (0.02–380.0 μM) and a narrow limit of detection (0.007 μM). The MoSe2 -rGO/SPCE was successful in sensing carbamazepine and amitriptyline in real specimens, with appreciable recovery rates. Graphical abstract: A novel electrochemical sensor for amitriptyline determination in the presence of carbamazepine was constructed. Image 1 Highlights: MoSe2 -rGO nanocomposite was synthesized. Screen printed electrode was modified with MoSe2 -rGO nanocomposite. The sensor successfully determined amitriptyline in the presence of carbamazepine.