The Pillow Sign: Is It Always Benign?. Issue 2 (26th February 2021)

• Record Type: Journal Article
• Authors: Alvencar, Sujay; Holzwanger, Erik; Dhingra, Rohit; Karagozian, Raffi; Olans, Lori; Natov, Nikola S.
• Is Part Of: ACG Case Reports Journal. Volume 8:Issue 2(2021)
• Page Start: e00540
• Publication Date: 2021-02-26
• DOI: 10.14309/crj.0000000000000540
• Languages: English
• ISSNs: 2326-3253

Abstract

ABSTRACT: Mucosa-associated lymphoid tissue (MALT) lymphoma is classically found in the stomach; however, in less common, cases can be found in extragastric locations. Colonic MALTomas are exceedingly rare and comprise a small group of extragastric cases. There is no standardized approach for optimal management of this disease. We report a case of a colonic MALT lymphoma found on colonoscopy that demonstrated the pillow sign and appearance of a benign lipoma. Despite antimicrobial and endoscopic therapy, the malignancy reoccurred in a patient with chronic hepatitis B, thereby precluding one of the mainstays of treatment, rituximab, until viral eradication.