Inflammation Biomarkers: Label‐Free Biophysical Markers from Whole Blood Microfluidic Immune Profiling Reveal Severe Immune Response Signatures (Small 12/2021). Issue 12 (25th March 2021)

• Record Type: Journal Article
• Authors: Zeming, Kerwin Kwek; Vernekar, Rohan; Chua, Mui Teng; Quek, Kai Yun; Sutton, Greg; Krüger, Timm; Kuan, Win Sen; Han, Jongyoon
• Is Part Of: Small. Volume 17:Issue 12(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-03-25
• Subjects: cell deformability -- deterministic lateral displacement -- immune profiling -- infection -- inflammation biomarkers; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.202170051
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : Host immune response plays a critical role in disease manifestation and severity. In article number 2006123, Win Sen Kuan, Jongyoon Han, and co‐workers present a whole blood biophysical immune response profiling tool using deterministic lateral displacement microfluidics. The speed and accuracy of immune response stratification demonstrated in an emergency department has a clear impact in enabling deployable point‐of‐care systems for rapid clinical triage.