Treatment of Nail Psoriasis with Intralesional Triamcinolone Acetonide Using a Needle-Free Jet Injector: A Prospective Trial. Issue 1 (January 2014)

• Record Type: Journal Article
• Authors: Nantel-Battista, Melissa; Richer, Vincent; Marcil, Isabelle; Benohanian, Antranik
• Is Part Of: Journal of cutaneous medicine and surgery. Volume 18:Issue 1(2014)
• Page Start: 38
• Page End: 42
• Publication Date: 2014-01
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Treatment -- Periodicals; Skin -- Surgery -- Periodicals; Dermatology -- Canada -- Periodicals; Skin -- Diseases -- Treatment -- Canada -- Periodicals; Skin -- Surgery -- Canada -- Periodicals; 616.5005
• DOI: 10.2310/7750.2013.13078
• Languages: English
• ISSNs: 1203-4754

Abstract

Background: Treating nail psoriasis is challenging. Corticosteroid matrix injection with needle is a conventional treatment but pain is often a limitation. Objective: Evaluate efficacy and safety of triamcinolone acetonide needle-free injection with the Med-Jet MBX in psoriatic fingernail. Methods: Seventeen patients were enrolled between January 2012 and January 2013. Four treatments sessions were scheduled every 4 ± 1 weeks. Clinical efficacy was evaluated according to Nail Psoriasis Severity Index (NAPSI) score of target nail differences before and after the treatment. Results: Mean baseline NAPSI score was 6.5 on an 8-point scale (95% confidence interval [CI] 5.652–7.348) and mean final NAPSI score was 2.8 on an 8-point scale (95% CI 1.859–3.741), demonstrating statistically significant treatment efficacy ( p =.0007). NAPSI score for target nail from baseline to end of treatment was decreased by 46.25%. Conclusion: Treatment with triamcinolone acetonide delivered by Med-Jet MBX is a safe, minimally painful and effective treatment for nail psoriasis.