Prevention of Staphylococcus Epidermidis Biofilm Formation Using Electrical Current. Issue 2 (May 2014)

• Record Type: Journal Article
• Authors: Del Pozo, Jose L.; Rouse, Mark S.; Euba, Gorane; Greenwood-Quaintance, Kerryl E.; Mandrekar, Jayawant N.; Steckelberg, James M.; Patel, Robin
• Is Part Of: Journal of applied biomaterials & functional materials. Volume 12:Issue 2(2014)
• Page Start: 81
• Page End: 83
• Publication Date: 2014-05
• Subjects: Electrical current -- Staphylococcus epidermidis -- Biofilm -- Electricidal effect; Biomedical materials -- Periodicals; Bioengineering -- Periodicals; Biomechanics -- Periodicals; 610.28
• DOI: 10.5301/jabfm.5000208
• Languages: English
• ISSNs: 2280-8000

Abstract

A technique for the prevention of staphylococcal adhesion by electrical current exposure was investigated. Teflon coupons were exposed to a continuous flow of 10 3 cfu/ml Staphylococcus epidermidis with or without 2000 microA DC electrical current delivered by electrodes on opposite sides of a coupon, touching neither each other nor the coupon. A mean 3.46 (SD, 0.20) and 5.70 (SD, 1.03) log10 cfu/cm 2 were adhered to the non-electrical current exposed coupons after 4 h and 24 h, respectively. A mean 2.46 (SD, 0.31) and 1.47 (SD, 0.73) log10 cfu/cm 2 were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by graphite electrodes. A mean 2.21 (SD, 0.14) and 0.55 (SD, 0.00) log10 cfu/cm 2 were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by stainless steel electrodes. Electrical current may be useful in the prevention of staphylococcal adhesion to biomaterials.