Acute Brain Stroke Evolution Detected by 18F-FDG PET/CT and MRI Justifies the Discordance of Lesions in a Patient With Lymphoproliferative Syndrome. (March 2021)

• Record Type: Journal Article
• Authors: Fernández-Rodríguez, Paula; Tamayo Carabaño, Daniella; Fernández López, Rosa; Piñero González de la Peña, Pilar; Borrego Dorado, Isabel
• Is Part Of: Clinical nuclear medicine. Volume 46:Number 3(2021)
• Page Start: e171
• Page End: e172
• Publication Date: 2021-03
• Subjects: 18F-FDG PET/CT -- hypermetabolic lesion -- MRI -- acute ischemic stroke -- lymphoproliferative syndrome; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000003486
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract: A 50-year-old man with angioimmunoblastic T-cell lymphoma in complete response to treatment presented new hypermetabolic brain lesions on 18 F-FDG PET/CT suggestive of malignancy. These findings were correlated by MRI that showed cortical-subcortical peripheral lesions typical of acute ischemic infarction. A restaging 18 F-FDG PET/CT showed that hypermetabolic lesions were replaced by ametabolic areas, supporting chronic infarction. Early ischemia presents transitory FDG increase. Brain lymphomas are highly FDG avid and difficult to differentiate from acute cerebral infarction. In view of the discordance of abnormal areas of intracranial uptake on PET FDG, MRI confirmation is required to avoid misinterpretation.