Emphysematous Gastritis in a Transplant Recipient With Clostridium ventriculi Infection. Issue 12 (8th December 2020)

• Record Type: Journal Article
• Authors: St. Michel, David Patrick; Borth, Amy; Rubin, Jonah; Goussous, Naeem; Twaddell, William; Malik, Saad; Barth, Rolf
• Is Part Of: ACG Case Reports Journal. Volume 7:Issue 12(2020)
• Page Start: e00488
• Publication Date: 2020-12-08
• DOI: 10.14309/crj.0000000000000488
• Languages: English
• ISSNs: 2326-3253

Abstract

ABSTRACT: Clostridium ventriculi is a rare infection in poorly controlled diabetic patients with a history of gastroparesis. We present the first documented case in a transplant recipient, who underwent a simultaneous liver kidney transplant. Computed tomography showed emphysematous gastritis, endoscopy revealed gastric necrosis, and microscopy confirmed the diagnosis. Operative intervention was high risk, given the previous liver transplant. Antibiotics and proton pump inhibitor treatment with repeat endoscopy at 4 days showed resolution of gastric necrosis and elimination of microscopic evidence of infection. Combination antibiotic and proton pump inhibitor therapy may be an effective treatment for this rare, life-threatening infection.