Strong ion analysis at the bedside. Issue 10 (October 2022)

• Record Type: Journal Article
• Authors: Loubser, Vera-Lisa; Hughes, Ryan; Brain, Matthew J.
• Is Part Of: Anaesthesia and intensive care medicine. Volume 23:Issue 10(2022)
• Page Start: 594
• Page End: 601
• Publication Date: 2022-10
• Subjects: Acid-base physiology -- carbon dioxide -- clinical chemistry -- hypoalbuminaemia -- strong ion theory; Anesthesiology -- Periodicals; Critical care medicine -- Periodicals; Anesthesia -- Periodicals; Intensive care -- Periodicals; Electronic journals; Periodicals; 617.9605
• DOI: 10.1016/j.mpaic.2022.07.011
• Languages: English
• ISSNs: 1472-0299

Abstract

Abstract: Quantitative physicochemical models of human acid-base physiology filled a void between clinical acid-base analysis and general fluid physiology. The physicochemical model is frequently perceived as too complex for bedside use, however a set of simplified screening questions based on Stewart's model can be utilized to aid acid-base interpretation. Emphasis is placed on understanding the acid-base consequences of hypoalbuminaemia, volume status, tonicity and chloride administration as these are common in intensive care unit patients.