Clinical outcome for heart failure hospitalizations in patients with leadless pacemaker. Issue 5 (28th July 2022)

• Record Type: Journal Article
• Authors: Katsuki, Tomonori; Nagashima, Michio; Kono, Hiroyuki; Sadohara, Yohei; Hirokami, Jun; Kuji, Rei; Korai, Kengo; Fukunaga, Masato; Hiroshima, Kenichi; Ando, Kenji
• Is Part Of: Journal of arrhythmia. Volume 38:Issue 5(2022)
• Page Start: 730
• Page End: 735
• Publication Date: 2022-07-28
• Subjects: heart failure hospitalization -- leadless pacemaker; Arrhythmia -- Periodicals; Cardiac pacing -- Periodicals; Arrhythmias, Cardiac; Arrhythmia; Cardiac pacing; Periodicals; Electronic journals; Periodicals; 616.128
• DOI: 10.1002/joa3.12761
• Languages: English
• ISSNs: 1880-4276

Abstract

Abstract: Introduction: The long‐term performance of leadless pacemaker (LPM) has not been well evaluated. Methods: Between September 2017 and January 2021, 929 consecutive patients who underwent pacemaker implantation were grouped according to the types of pacemakers: LPM (LPM group, n = 368) and conventional pacemaker (PM group, n = 561). Results: The median follow‐up duration was 1.7 years (interquartile range 0.8–2.6 years). Hospitalization rate for heart failure in the LPM group was 9.3%, 15.6%, and 21.6% at 1, 2, 3 years, respectively. The LPM group had a significantly higher adjusted heart failure hospitalization risk than the PM group [hazard ratio (HR) 1.70, 95% confidence interval (CI) 1.09–2.64, p = .01]. More patients with symptomatic bradycardia caused by sinus node dysfunction (SND) in the LPM group ( n = 150) were admitted to the hospital for heart failure compared to those in the PM group ( n = 219) (HR 2.02, 95%CI 1.04–3.90, p = .03), whereas no significant difference was observed between the two groups in the patients with bradycardia caused by atrial fibrillation (LPM group, n = 71; PM group, n = 18) or atrioventricular block (LPM group, n = 147; PM group, n = 324). Conclusions: Patients who received LPM implantation had greater hospitalization risk for heart failure, compared to those who received conventional pacemaker implantation. The increased risk was mainly attributed to patients with SND.