Acute Ischemic Stroke Secondary to Glioblastoma: A Case Report. Issue 1 (February 2014)

• Record Type: Journal Article
• Authors: Pina, Sofia; Carneiro, Ângelo; Rodrigues, Tiago; Samões, Raquel; Taipa, Ricardo; Melo-Pires, Manuel; Pereira, Cláudia
• Is Part Of: Neuroradiology journal. Volume 27:Issue 1(2014)
• Page Start: 85
• Page End: 90
• Publication Date: 2014-02
• Subjects: glioblastoma -- stroke -- vasculopathy -- computed tomography -- magnetic resonance imaging; Nervous system -- Radiography -- Periodicals; Neuroradiography -- Periodicals; Electronic journals; 616.804757
• DOI: 10.15274/NRJ-2014-10009
• Languages: English
• ISSNs: 1971-4009

Abstract

Glioblastoma is a malignant infiltrative glial tumor occurring most often over 50 years of age, with diverse clinical presentations. We describe a case of temporal lobe glioblastoma with a rare presentation as an acute ischemic stroke, discussing the imaging and histopathological findings, and reviewing the literature. A 77-year-old woman had sudden onset of left hemiparesis and hemihypoesthesia. The neuroradiological studies revealed an acute ischemic lesion in the right lenticulostriate arteries territory and a right anterior temporal lobe tumor, enhancing heterogeneously after contrast with enhancement of the right middle cerebral artery wall. Histopathological analysis of the resected temporal lesion revealed a glioblastoma multiforme with tumoral infiltration of the vascular wall. Glioblastoma should be considered in the etiology of acute ischemic stroke, where neuroimaging plays an important diagnostic role, enabling a more immediate therapeutic approach, with a consequent impact on survival.