Evaluation of evidence supporting NICE recommendations to change people's lifestyle in clinical practice: cross sectional survey. Issue 1 (14th September 2022)

• Record Type: Journal Article
• Authors: Albarqouni, Loai; Ringsten, Martin; Montori, Victor; Jørgensen, Karsten Juhl; Bulbeck, Helen; Johansson, Minna
• Is Part Of: BMJ medicine. Volume 1:Issue 1(2022)
• Publication Date: 2022-09-14
• Subjects: health policy; Medicine -- Periodicals; 610
• DOI: 10.1136/bmjmed-2022-000130
• Languages: English
• ISSNs: 2754-0413

Abstract

Abstract : Objectives: To assess whether recommendations of individually oriented lifestyle interventions (IOLIs) in guidelines from the National Institute for Health and Care Excellence (NICE) were underpinned by evidence of benefit, and whether harms and opportunity costs were considered. Design: Cross sectional survey. Setting: UK. Data sources: NICE guidelines and supporting evidence. Eligibility criteria: All NICE pathways for IOLI recommendations (ie, non-drug interventions that healthcare professionals administer to adults to achieve a healthier lifestyle and improve health) were searched systematically on 26 August 2020. One author screened all retrieved pathways for candidate guidelines, while a second author verified these judgments. Two authors independently and in duplicate screened all retrieved guidelines and recommendations for eligibility, extracted data, and evaluated the evidence cited and the outcomes considered. Disagreements were noted and resolved by consensus. Results: Within 57 guidelines, 379 NICE recommendations were found for IOLIs; almost all (n=374; 99%) recommended the lifestyle intervention and five (1%) recommended against the intervention. Of the 379 recommendations, 13 (3%) were supported by moderate or high certainty evidence of a beneficial effect on patient relevant outcomes (n=7; 2%) or surrogate outcomes (n=13; 3%). 19 (5%) interventions considered psychosocial harms, 32 (8%) considered physical harms, and one (<1%) considered the opportunity costs of implementation. No intervention considered the burden placed on individuals by these recommendations. Conclusion: Few NICE recommendations of lifestyle interventions are supported by reliable evidence. While this finding does not contest the beneficial effects of healthy habits, guidelines recommending clinicians to try to change people's lifestyle need to be reconsidered given the substantial uncertainty about the effectiveness, harms, and opportunity costs of such interventions.