Capturing complex interactions in disease ecology with simplicial sets. (24th August 2022)

• Record Type: Journal Article
• Authors: Silk, Matthew J.; Wilber, Mark Q.; Fefferman, Nina H.
• Is Part Of: Ecology letters. Volume 25:Number 10(2022)
• Page Start: 2217
• Page End: 2231
• Publication Date: 2022-08-24
• Subjects: dose–response -- ecological network -- epidemiological model -- higher‐order interaction -- hypergraph -- movement network -- simplicial complex -- social network; Ecology -- Periodicals; 577
• DOI: 10.1111/ele.14079
• Languages: English
• ISSNs: 1461-023X

Abstract

Abstract: Network approaches have revolutionized the study of ecological interactions. Social, movement and ecological networks have all been integral to studying infectious disease ecology. However, conventional (dyadic) network approaches are limited in their ability to capture higher‐order interactions. We present simplicial sets as a tool that addresses this limitation. First, we explain what simplicial sets are. Second, we explain why their use would be beneficial in different subject areas. Third, we detail where these areas are: social, transmission, movement/spatial and ecological networks and when using them would help most in each context. To demonstrate their application, we develop a novel approach to identify how pathogens persist within a host population. Fourth, we provide an overview of how to use simplicial sets, highlighting specific metrics, generative models and software. Finally, we synthesize key research questions simplicial sets will help us answer and draw attention to methodological developments that will facilitate this. Abstract : We present simplicial sets as a tool to study higher‐order interactions in disease ecology focussing on applications in social, spatial and host‐pathogen networks. We synthesise key research questions simplicial sets will help us answer and highlight methodological developments that can facilitate this.