Feasibility of oncology clinical trial‐embedded evaluation of social determinants of health. Issue 11 (7th September 2022)

• Record Type: Journal Article
• Authors: Aziz‐Bose, Rahela; Zheng, Daniel J.; Umaretiya, Puja J.; Ilcisin, Lenka; Stevenson, Kristen; Koch, Victoria; Valenzuela, Ariana; Cole, Peter D.; Gennarini, Lisa M.; Kahn, Justine M.; Kelly, Kara M.; Tran, Thai‐Hoa; Michon, Bruno; Welch, Jennifer J. G.; Silverman, Lewis B.; Wolfe, Joanne; Bona, Kira
• Is Part Of: Pediatric blood & cancer. Volume 69:Issue 11(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-09-07
• Subjects: health equity -- research methods -- social determinants of health; Tumors in children -- Periodicals; Blood -- Diseases -- Periodicals; Cancer in children -- Periodicals; 618.92
• DOI: 10.1002/pbc.29933
• Languages: English
• ISSNs: 1545-5009

Abstract

Abstract: Social determinants of health (SDoH) are associated with stark disparities in cancer outcomes, but systematic SDoH data collection is virtually absent from oncology clinical trials. Trial‐based SDoH data are essential to ensure representation of marginalized populations, contextualize outcome disparities, and identify health‐equity intervention opportunities. We report the feasibility of a pediatric oncology multicenter therapeutic trial‐embedded SDoH investigation. Among 448 trial participants, 392 (87.5%) opted‐in to the embedded SDoH study; 375 (95.7%) completed baseline surveys, with high longitudinal response rates (88.9–93.1%) over 24 months. Trial‐embedded SDoH data collection is feasible and acceptable and must be consistently included within future oncology trials.