Diagnosis and Management of Valvular Aortic Stenosis. Issue 8 (January 2014)

• Record Type: Journal Article
• Authors: Czarny, Matthew J.; Resar, Jon R.
• Is Part Of: Clinical Medicine Insights. Issue 8(2014)Supplement 1
• Publication Date: 2014-01
• Subjects: valvular aortic stenosis -- surgical aortic valve replacement -- transcatheter aortic valve replacement -- balloon aortic valvuloplasty -- aortic stenosis therapy; Cardiovascular system -- Diseases -- Periodicals; Cardiology -- Periodicals; Cardiovascular Diseases; Cardiology; Cardiovascular system -- Diseases; Electronic journals; Periodicals; Fulltext; Internet Resources; Periodicals; Periodicals; 616.12
• DOI: 10.4137/CMC.S15716
• Languages: English
• ISSNs: 1179-5468

Abstract

Valvular aortic stenosis (AS) is a progressive disease that affects 2% of the population aged 65 years or older. The major cause of valvular AS in adults is calcification and fibrosis of a previously normal tricuspid valve or a congenital bicuspid valve, with rheumatic AS being rare in the United States. Once established, the rate of progression of valvular AS is quite variable and impossible to predict for any particular patient. Symptoms of AS are generally insidious at onset, though development of any of the three cardinal symptoms of angina, syncope, or heart failure portends a poor prognosis. Management of symptomatic AS remains primarily surgical, though transcatheter aortic valve replacement (TAVR) is becoming an accepted alternative to surgical aortic valve replacement (SAVR) for patients at high or prohibitive operative risk.