Recent advances and approaches in the metal-free synthesis of 1, 3-oxazole derivatives. Issue 17 (2nd September 2022)

• Record Type: Journal Article
• Authors: Shinde, Suraj; Inamdar, Shaukatali; Shinde, Mahadev; Kushwaha, Narvadeshwar; Obakachi, Vincent; Girase, Pankaj; Kushwaha, Babita; Dhawan, Sanjeev; Kumar, Vishal; Karpoormath, Rajshekhar
• Is Part Of: Synthetic communications. Volume 52:Issue 17(2022)
• Page Start: 1685
• Page End: 1704
• Publication Date: 2022-09-02
• Subjects: Metal-free synthesis -- nonmetal dependent synthesis -- 1, 3-oxazole derivatives; Organic compounds -- Synthesis -- Periodicals; Chemistry, Organic; Synthesis; 547.205
• DOI: 10.1080/00397911.2022.2107432
• Languages: English
• ISSNs: 0039-7911

Abstract

Abstract: This review presents an overview of recent advances and approaches in the metal-free synthesis of substituted 1, 3-oxazole derivatives, which will enable organic researchers to identify the challenges in synthesizing these five-membered heterocyclic compounds. Specifically, 1, 3-oxazole moiety containing compounds have been reported to possess a wide variety of applications, including in the medicinal, pharmaceutical, agrochemical and material sciences sectors. We classified these nonmetal-catalyzed synthetic approaches on the basis of their starting material's functionality that was used to synthesize 1, 3-oxazole. This review covers the last six-year (2016–2021) of nonmetal catalyzed/mediated synthetic approaches. Graphical Abstract: UF0001