Cytology of malignant pleural mesothelioma: Diagnostic criteria, WHO classification updates, and immunohistochemical staining markers diagnostic value. Issue 11 (7th September 2022)

• Record Type: Journal Article
• Authors: Shaker, Nada; Wu, Douglas; Abid, Abdul Majeed
• Is Part Of: Diagnostic cytopathology. Volume 50:Issue 11(2022)
• Page Start: 532
• Page End: 537
• Publication Date: 2022-09-07
• Subjects: classification -- cytopathology -- epithelioid -- lung -- mesothelioma -- pleural effusion -- reactive mesothelial proliferation -- sarcomatoid; Cytodiagnosis -- Periodicals; Pathology, Cellular -- Periodicals; Cytology -- Periodicals; 616.07582
• DOI: 10.1002/dc.25053
• Languages: English
• ISSNs: 8755-1039

Abstract

Abstract: Malignant pleural mesothelioma (MPM) is a rare but aggressive malignancy with a poor prognosis. Because of this tumor rarity and overlapping histologic features with other malignancy types, the histopathological findings and diagnostic immunohistochemical workup are essential in establishing the final diagnosis of MPMs. We aimed to review the diagnostic criteria, WHO tumor classification updates, and immunohistochemical staining markers diagnostic value to achieve an appropriate clinical diagnosis.