Assessment of late gadolinium enhancement-negative chronic total occlusion by longitudinal strain analysis using cardiac magnetic resonance imaging. (December 2022)

• Record Type: Journal Article
• Authors: Zhang, Chen; Li, Xin; Mou, Anna; Huang, RongChong; Song, Qingwei; Liu, Ailian; Li, Zhiyong
• Is Part Of: Acta radiologica. Volume 63:Number 12(2022)
• Page Start: 1634
• Page End: 1642
• Publication Date: 2022-12
• Subjects: Cardiac magnetic resonance -- chronic total occlusion -- feature tracking -- longitudinal strain; Radiology, Medical -- Periodicals; Radiography, Medical -- Periodicals; Radiotherapy -- Periodicals; 616.0757
• DOI: 10.1177/02841851211055395
• Languages: English
• ISSNs: 0284-1851

Abstract

Background: Strain analysis has become commonly used in clinical practice in various heart diseases. Purpose: To explore whether late gadolinium enhancement (LGE)-negative areas with coronary artery chronic total occlusion (CTO) appear normal when analyzed for longitudinal strain using cardiac magnetic resonance (CMR) imaging. Material and Methods: A total of 16 patients and 31 healthy controls who underwent 1.5-T MR at our hospital between January 2015 and July 2017 were included in the study. The LGE-CMR of patients with CTO was negative. Left ventricular functional parameters, segmental longitudinal strain/strain rate, and perfusion parameters were measured using CVI42 software. Results: For myocardial segments supplied by CTO vessels, systolic longitudinal strain rate (SLSR)was significantly lower than that of healthy controls, and diastolic longitudinal strain rate (DLSR) was significantly higher (1.19 1/s vs. 1.02 1/s; P = 0.018). Moreover, longitudinal strain (LS), SLSR, and DLSR did not differ between good and poor collateral circulation. Perfusion index of CTO territory segments was lower than non-CTO territory segments (0.20 vs. 0.22; P = 0.027). No correlation was found between longitudinal strain parameters and perfusion parameters. Conclusion: Although LGE-CMR was negative in patients with CTO, the myocardial SLSR of CTO territory segments was significantly lower than that of healthy controls.