Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 Delta Variant Shedding in a Patient With AIDS: Case Report and Review of the Literature. (17th September 2022)

• Record Type: Journal Article
• Authors: Peters, Jillian L; Fall, Amary; Langerman, Steven D; El Asmar, Margueritta; Nakazawa, Mari; Mustapha, Aishat; Tobian, Aaron A R; Mostafa, Heba H; Blankson, Joel N
• Is Part Of: Open forum infectious diseases. Volume 9:Number 9(2022)
• Publication Date: 2022-09-17
• Subjects: COVID-19; SARS-CoV2 -- PLWH -- HIV; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofac479
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: We describe the case of a patient with AIDS who had persistent infection with a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant for >80 days. The variant contained mutations that were not present in other Delta viruses in our hospital. Prolonged infection in immunosuppressed individuals may lead to evolution of SARS-CoV-2 lineages.