Circulation of an Artemisinin-Resistant Malaria Lineage in a Traveler Returning from East Africa to France . (25th February 2022)

• Record Type: Journal Article
• Authors: Coppée, Romain; Bailly, Justine; Sarrasin, Véronique; Vianou, Bertin; Zinsou, Boris Enock; Mazars, Edith; Georges, Hugues; Hamane, Samia; Lavergne, Rose Anne; Dannaoui, Eric; Balikagala, Betty; Fukuda, Naoyuki; Odongo-Aginya, Emmanuel I; Mita, Toshihiro; Houzé, Sandrine; Clain, Jérôme
• Is Part Of: Clinical infectious diseases. Volume 75:Number 7(2022)
• Page Start: 1242
• Page End: 1244
• Publication Date: 2022-02-25
• Subjects: Plasmodium falciparum -- kelch13 -- artemisinin resistance -- East Africa -- whole-genome sequencing; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciac162
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: A returned traveler to Uganda presented with a Plasmodium falciparum kelch13 A675V mutant infection that exhibited delayed clearance under artesunate therapy. Parasites were genetically related to recently reported Ugandan artemisinin-resistant A675V parasites. Adequate malaria prevention measures and clinical and genotypic surveillance are important tools to avoid and track artemisinin resistance.