CHANGES OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY PARAMETERS AFTER INTERNAL LIMITING MEMBRANE PEELING COMPARED WITH NONPEELING IN EPIRETINAL MEMBRANE SURGERY. Issue 10 (October 2022)

• Record Type: Journal Article
• Authors: Gabriel, Maximilian; Djavid, Daniel; Innauer, Felix; Ivastinovic, Domagoj; Seidel, Gerald; Mayer-Xanthaki, Christoph; Ansari-Shahrezaei, Siamak; Wedrich, Andreas; Haas, Anton
• Is Part Of: Retina. Volume 42:Issue 10(2022)
• Page Start: 1867
• Page End: 1873
• Publication Date: 2022-10
• Subjects: epiretinal membrane -- vitrectomy -- internal limiting membrane peeling -- optical coherence tomography angiography; Retina -- Diseases -- Periodicals; Retinal Diseases; Vitreous Body; 617.735
• DOI: 10.1097/IAE.0000000000003567
• Languages: English
• ISSNs: 0275-004X

Abstract

Abstract : Mean superficial capillary plexus foveal avascular zone area and mean superficial capillary plexus parafoveal vessel density increased more after internal limiting membrane nonpeeling compared with peeling in epiretinal membrane surgery after three months. Abstract : Purpose: To prospectively compare microvascular changes of internal limiting membrane (ILM) peeled and nonpeeled eyes in patients with idiopathic epiretinal membranes using optical coherence tomography angiography. Methods: Forty-two patients with epiretinal membranes underwent vitrectomy with (n = 22) or without ILM peeling (n = 20). The mean superficial capillary plexus foveal avascular zone area change between preoperative and three-month postoperative readings served as the main outcome measure. Secondary outcome parameters included mean changes in superficial capillary plexus parafoveal vessel density, central foveal thickness, retinal volume, and best-corrected visual acuity. Results: Mean superficial capillary plexus foveal avascular zone area change (μm 2 ) was 59 ± 74 in the ILM nonpeeling group compared with −12 ± 86 in the ILM peeling group ( P = 0.007). Similarly, mean superficial capillary plexus parafoveal vessel density change (%) was higher in the ILM nonpeeling group (ILM nonpeeling 4 ± 4, ILM peeling −2 ± 6, P = 0.003). The mean retinal volume reduction was higher in the ILM peeling group, and this difference also reached statistical significance ( P = 0.036). There were no intergroup differences in mean central foveal thickness change and mean best-corrected visual acuity change ( P = 0.409 and P = 0.440, respectively). Epiretinal membrane/ILM separation was achieved in 23 of 51 patients. Conclusion: The macular microvasculature demonstrated more remodeling in the ILM nonpeeling group after three months.